Abstract: The general features and seasonal variation of mesoscale eddies in the Bay of Bengal from 1993 to 2016 are analyzed based on the latest data set of mesoscale eddies provided by AVISO. The result shows that there are 822 cyclones and 731 anticyclones in the Bay of Bengal, and they mostly distribute in the north of 15°N in the Bay of Bengal and the Andaman Sea. Eddy lifetimes are mainly ranged from 28 to 59 days. Cyclones and anticyclones have an average amplitude and radius of 7.5 cm and 119.6 km, respectively. The amplitude has two peaks in 6°-9°N and 15°-20°N and the average radius of eddies gradually decreases with increasing latitude. The amplitude and radius of the eddy grows slowly and dissipates fast during the evolution of eddy. Cyclones and anticyclones mainly move to westward and tend to move toward the equator. The mesoscale eddies with a longer lifetime (more than 60 days) have an obviously seasonal variation in the Bay of Bengal, and the eddies are mostly generated in spring, the next in winter and the less in summer. The synthetic analysis concludes that the wind stress curl is an important reason for the seasonal variation of the mesoscale eddies and the westward propagating Rossby wave radiated by coastal Kelvin wave has a certain influence on the generation of mesoscale eddy in the Bay of Bengal. The analysis of eddy kinetic energy indicates that the high value zone of eddy kinetic energy is mainly located in the western boundary of the basin and in the east of Sri Lanka, while the region with strong eddy activity corresponds well with the larger eddy kinetic energy in winter and spring in the western boundary of the basin and in summer and autumn in the north of the basin.