Abstract: Response of three-dimensional fields of temperature, salinity and dissolved oxygen (DO) to typhoons in the northwestern Pacific was analyzed by a composing analytical method based on 20-year Argo buoy data. The results show that on the right side of typhoon tracks, sea surface temperature showed significant negative anomalies, i.e. being a “right-hand-side intensification”, while in the subsurface layer, it is mixed with positive and negative anomalies due to both heat pump effect and the cold suction effect. In the layers below the subsurface, it is dominated by negative temperature anomalies, while the “right-hand-side intensification” is not obvious. From surface to the depth of 1 000 m, vertical distribution of salinity anomaly of each layer represents a “positive-negative-positive” variation feature. At each horizontal layer below surface, salinity anomaly field is more uniform in both parallel and perpendicular to the direction of typhoon track. From surface to 1 000 m depth, concentrations of DO represent “low-high-little” distribution. Horizontal distribution of DO in each layer is similar, that is, there exists a high value band area along the typhoon track. Response of average depth of temperature, salinity and DO to typhoon can penetrate more than 1 000 m according to the composing results.